Murine Anti-Factor IX

Clone GMA-101

Background

Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Absent or defective FIX is the cause of the X-linked recessive bleeding disorder hemophilia B. GMA-101 binds to FIX and FIXa in ELISA assays.

Description

  • Species Reactivity:
    Human
  • Source:
    Murine
  • Specificity:
    FIX/FIXa
  • Immunogen:
    Human Factor IX
  • Isotype:
    IgG1

Application

  • ELISA:
    Binds immobilized Human FIX/IXa.
  • Immunoblotting:
    Not recommended for Western blotting.
  • Inhibition:
    Does not prolong plasma clot time in APTT clotting assay.

GMA-101

$240.00$600.00

Buy: GMA-101
0.5 mg/$600.00 0.1 mg/$240.00
For larger volumes, please call.
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