Murine Anti-Factor V
Factor V (FV) circulates in blood as a single chain protein (Mr 330,000). Following proteolytic activation by thrombin, activated factor V (FVa) serves as the cofactor for factor Xa in the prothrombinase complex that cleaves prothrombin to thrombin in the presence of phospholipid and Ca2+. Factor Va is composed of a heavy chain (Mr 94,000) non-covalently associated to a light chain (Mr 74,000). GMA-5007 recognizes the activation fragment of FVa,1 binds FV and FVa under reduced and non-reduced conditions,and can be used for purification of the activation fragment.1
- Species Reactivity:Human
- Specificity:FV, FVa activation fragment
- Immunogen:Human Factor V
- ELISA:Binds immobilized human FV and FVa.
- Immunoblotting:Binds Factor V and factor Va under reduced and non-reduced conditions.
- Inhibition:Not inhibitory in aPTT clotting assay.
$265.00 – $660.00