GMA-142
Murine Anti- Factor XII Heavy Chain
Clone GMA-142
Background
Factor XII, also known as Hageman factor, is an activator of both coagulation and the kinin system. During contact activation, factor XII (Mr 80,000) is proteolytically cleaved at several sites, creating activated factor XIIa. Factor XIIa cleaves prekallikrein to kallikrein and factor XI to factor XIa. GMA-142 binds FXII in ELISA and Western blot, and pairs with other GMA antibodies.
More Information:
Product Datasheet, pdfDescription
Species Reactivity: Human
Source: Murine
Specificity: Factor XII Heavy Chain
Immunogen: Human Factor XII
Isotype: IgG1
Application
ELISA: binds immobilized factor XII
Immunoblotting: Binds human FXII and XIIa heavy chain under reduced and non-reduced conditions.
Data:
