GMA-145
Murine Anti- Factor XII
Clone GMA-145
Background
Factor XII, also known as Hageman factor, is an activator of both coagulation and the kinin system. During contact activation, factor XII (Mr 80,000) is proteolytically cleaved at several sites, creating activated factor XIIa. Factor XIIa cleaves prekallikrein to kallikrein and factor XI to factor XIa. GMA-145 binds FXII in Western blot and can be paired with GMA-140.
More Information:
Product Datasheet, pdfDescription
Species Reactivity: Human
Source: Murine
Specificity: Factor XII
Immunogen: Human Factor XII
Isotype: IgG2b
Application
ELISA: Not recommended.
Immunoblotting: Binds human FXII and XIIa under non-reduced conditions.
Data:
