Antibody Summary Page:Factor IX
Factor IX in plasma is a single chain protein (Mr 55,000) and contains the vitamin K-dependent amino acid γ-carboxyglutamic acid. Activation of factor IX by factor XIa removes a 35 amino acid activation peptide to give a two-chain structure consisting of a light chain disulfide-bonded to a heavy chain. Factor IXa is the enzyme of the tenase complex which activates factor X to Xa in the presence of cofactor factor VIIIa, phospholipid and Ca2+.
Click here for a summary table of Anti-Factor IX Antibodies.