GMA-146
Murine Anti- Factor XII
Clone GMA-146
Background
Factor XII (FXII), also known as Hageman factor, is an activator of both coagulation and the kinin system. During contact activation, factor XII (Mr 80,000) is proteolytically cleaved at several sites, creating activated factor XIIa. Factor XIIa cleaves prekallikrein to kallikrein and factor XI to factor XIa. GMA-146 binds FXII in ELISA and Western blot and can be paired with GMA-140.
More Information:
Product Datasheet, pdfDescription
Species Reactivity: Human
Source: Murine
Specificity: Factor XII/XIIa
Immunogen: Human Factor XII
Isotype: IgG1
Application
ELISA: Not recommended.
Immunoblotting: Binds human FXII and XIIa under non-reduced conditions.
Data:
