Murine Anti- Factor V
Factor V (FV) circulates in blood as a single chain protein (Mr 330,000). Following proteolytic activation by thrombin, activated factor V (FVa) serves as the cofactor for factor Xa in the prothrombinase complex that cleaves prothrombin to thrombin in the presence of phospholipid and Ca2+. Factor Va is composed of a heavy chain (Mr 94,000) non-covalently associated to a light chain (Mr 74,000). GMA-5007 recognizes the activation fragment of FVa,1 binds FV and FVa under reduced and non-reduced conditions,and can be used for purification of the activation fragment.1
More Information:Product Datasheet, pdf
Species Reactivity: Human
Specificity: FV, FVa activation fragment
Immunogen: Human Factor V
ELISA: Binds immobilized human FV and FVa.
Immunoblotting: Binds Factor V and factor Va under reduced and non-reduced conditions.
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