Murine Anti- Factor VIII

Clone GMA-8045


Factor VIII (FVIII) is a heterodimer consisting of a heavy chain (ranging in mass from 90 to 200 kDa) bound via metal ions to a light chain (80 kDa). In plasma, FVIII circulates in an inactive form bound to von Willebrand factor. Following activation by factor Xa or thrombin, factor VIIIa can function as cofactor for the enzyme factor IXa in the activation of factor X in the presence of phospholipid and Ca2+. Absent or defective FVIII is the cause of the X-linked recessive bleeding disorder hemophilia A. GMA-8045 is suitable for ELISA applications.

More Information:

Product Datasheet, pdf


Species Reactivity: Human
Source: Murine
Specificity: Light Chain
Immunogen: Recombinant human FVIII light chain (residues 1689-2332)
Isotype: IgG1


ELISA: Binds immobilized human FVIII.
Immunoblotting: Not recommended.


ELISA validation data for clone GMA-8045

Purchase GMA-8045

  • 0.5 mg/$660.00
  • 0.1 mg/$265.00
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