Antibodies for Detection and Neutralization of Biotherapeutics
There is a need for antibodies in pre-clinical and clinical studies for the detection of potential biotherapeutic antibodies (Th-Mab)
and also for the blocking of the therapeutic to its specific ligand target (anti-idiotypic/neutralizing (anti-ID Nab)).
As there is a potential for adverse effects on the animal’s immune system from either the active drug-antigen and/or resulting circulating antibody during the immunization phase, specifically designed immunization protocols are used to abrogate potential adverse effects.
