Recombinant Antibody Production: Technology, Benefits, and Use Cases

Recombinant antibody production is transforming the way scientists develop, optimize, and apply monoclonal antibodies. Unlike traditional hybridoma-derived antibodies, recombinant monoclonal antibodies are generated using precise genetic information, enabling unparalleled control over specificity, consistency, and scalability. In this post, we break down the fundamentals of recombinant antibody technology, outline the production workflow, and explore why this […]

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Timeline & Cost Factors in Custom Monoclonal Antibody Development

Understanding the timeline and cost of custom monoclonal antibody development is essential for research and biotech teams planning new assays, diagnostics, or therapeutic projects. Whether you need small-scale R&D quantities or a robust development pipeline, knowing what drives price and turnaround time helps you make informed decisions—and avoid delays. In this guide, we break down […]

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Hybridoma Technology Explained: The Backbone of Monoclonal Antibody Production

Hybridoma technology is a cornerstone of modern biomedical research and diagnostic development. It enables the large-scale production of monoclonal antibodies—highly specific proteins that recognize a single epitope on a target antigen. Whether you’re working in basic research, therapeutic development, or in vitro diagnostics, understanding how hybridomas work can inform better decisions around antibody sourcing and […]

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How Mouse Monoclonal Antibodies Are Made: A Step-by-Step Overview

Monoclonal antibodies have become indispensable tools in biomedical research, diagnostics, and therapeutic development. Among the various production methods, the use of mouse models remains a gold standard for generating high-affinity, antigen-specific monoclonal antibodies. In this article, we walk through how monoclonal antibodies are made, focusing specifically on the well-established process of mouse monoclonal antibody development […]

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Choosing the Right Antibody Production Partner in the U.S.

Selecting a trusted provider for custom antibody production in the USA is a pivotal step in ensuring the success of your research, diagnostics, or therapeutic development. Whether you’re looking for high-specificity monoclonal antibodies or high-yield polyclonal antibodies, your choice of partner directly impacts data reliability, project timelines, and downstream applications. At Green Mountain Antibodies, we […]

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Recombinant Expression Validates De Novo Sequencing Accuracy: Trastuzumab & Anti-Factor XII Case Study

Husseini, I.3, Ruiz, A.3, Mitchell, M.1, Wenzel, R.2, Nazabal, A.3, Feldman, H.M.1 1Green Mountain Antibodies, Burlington, VT 05401 2 CovalX Analytics Inc., Woburn, MA 01801 3 CovalX Analytics SA, Martillac, France 33650 Introduction In this case study, we evaluated the accuracy and functionality of sequences derived from two reference antibodies: anti-HER2 (trastuzumab) and anti–Factor XII […]

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Mouse Monoclonal vs. Rabbit Polyclonal Antibodies: Which Is Right for Your Research?

Selecting the appropriate antibody—mouse monoclonal or rabbit polyclonal—can significantly shape the success of your experiments. Each antibody type plays a distinct role in biomedical research and diagnostics, with clear strengths and limitations. At Green Mountain Antibodies, we specialize in helping scientists and biotech teams make data-driven decisions to ensure reliable, reproducible results. What Are Mouse […]

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