GMA-101

Murine Anti- Factor IX

Clone GMA-101

Background

Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Absent or defective FIX is the cause of the X-linked recessive bleeding disorder hemophilia B. GMA-101 binds to FIX and FIXa in ELISA assays.

More Information:

Product Datasheet, pdf

Description

Species Reactivity: Human
Source: Murine
Immunogen: Human Factor IX
Isotype: IgG1

Application

ELISA: Binds the A2 domain of human factor VIII and human factor VIIIa.
Immunoblotting: Not recommended.
Inhibition: Does not prolong plasma clot time in APTT clotting assay.

Data:

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  • 0.1 mg/$265.00
  • 0.5 mg/$660.00
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