GMA-101
Murine Anti- Factor IX
Clone GMA-101
Background
Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Absent or defective FIX is the cause of the X-linked recessive bleeding disorder hemophilia B. GMA-101 binds to FIX and FIXa in ELISA assays.
More Information:
Product Datasheet, pdfDescription
Species Reactivity: Human
Source: Murine
Specificity: FIX/FIXa
Immunogen: Human Factor IX
Isotype: IgG1
Application
ELISA: Binds immobilized Human FIX/IXa.
Immunoblotting: Not recommended.
Inhibition: Does not prolong plasma clot time in APTT clotting assay.
Data:
