Murine Anti- Factor V
Factor V (FV) circulates in blood as a single chain protein (Mr 330,000). Following proteolytic activation by thrombin, activated factor V (FVa) serves as the cofactor for factor Xa in the prothrombinase complex that cleaves prothrombin to thrombin in the presence of phospholipid and Ca2+. Factor Va is composed of a heavy chain (Mr 94,000) non-covalently associated to a light chain (Mr 74,000). GMA-5001 (previously known as GMA-081) recognizes the light chain of FVa and is inhibitory in aPTT-based clotting assays.
More Information:Product Datasheet, pdf
Not sure what you need?
Our expert team will guide you every step of the way.