Murine Anti- Factor X

Clone GMA-529


Factor X (Mr 59,000) is a vitamin K-dependent plasma protein zymogen that plays a central role as the substrate for both the intrinsic (factor VIIa, tissue factor) and extrinsic (factor IXa, factor VIIIa) pathways. In the presence of cofactor factor Va, phospholipid, and Ca2+, activated factor X cleaves two peptide bonds in prothrombin to form thrombin. GMA-529 (also known as α-HFX-27) binds human factor X and Xa in solid-phase ELISA and Western blot. GMA-529 prolonged FX-dependent clotting time, and activated partial thromboplastin time of normal plasma, and showed inhibition of thrombin generation.1

More Information:

Product Datasheet, pdf


Species Reactivity: Human
Source: Murine
Specificity: Factor X/Xa
Immunogen: Human Factor X
Isotype: IgG1


ELISA: Binds immobilized human factor X and factor Xa. Does not bind mouse FX.
Immunoblotting: Binds human factor X and Xa under non-reduced conditions. Does not blot reduced FX/Xa.
Inhibition: Inhibits thrombin generation, prolongs clotting time.1


Purchase GMA-529

  • 0.5 mg/$660.00
  • 0.1 mg/$265.00
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