Murine Anti- Factor X
Factor X (Mr 59,000) is a vitamin K-dependent plasma protein zymogen that plays a central role as the substrate for both the intrinsic (factor VIIa, tissue factor) and extrinsic (factor IXa, factor VIIIa) pathways. In the presence of cofactor factor Va, phospholipid, and Ca2+, activated factor X cleaves two peptide bonds in prothrombin to form thrombin. GMA-529 (also known as α-HFX-27) binds human factor X and Xa in solid-phase ELISA and Western blot. GMA-529 prolonged FX-dependent clotting time, and activated partial thromboplastin time of normal plasma, and showed inhibition of thrombin generation.1
More Information:Product Datasheet, pdf
Not sure what you need?
Our expert team will guide you every step of the way.