GMA-138
Murine Anti- Factor IX
Clone GMA-138
Background
Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Defect or deficiencies in FIX lead to the X-linked recessive bleeding disorder hemophilia B. GMA-138 binds to FIX and FIXa in ELISA assays, and bound GMA-138 detects human FIX by bio-layer interferometry.
More Information:
Product Datasheet, pdfDescription
Species Reactivity: Bovine, Human, Porcine, Rat
Source: Murine
Specificity: FIX/IXa
Isotype: IgG1
Application
ELISA: Binds immobilized Human, Bovine, Porcine, and Rat FIX and Human FIXa
Immunoblotting: Not recommended for Western blotting.
Inhibition: Does not prolong plasma clot time in APTT clotting assay.
Data:
