Protein C Antibody Summary
Protein C is a vitamin K–dependent plasma glycoprotein that plays a critical role in the regulation of blood coagulation. Synthesized in the liver, Protein C circulates in plasma as an inactive zymogen and is activated to activated Protein C (APC) through proteolytic cleavage by the thrombin–thrombomodulin complex on endothelial cell surfaces.
Once activated, APC serves as a potent anticoagulant by inactivating Factors Va and VIIIa, thereby downregulating thrombin generation and preventing excessive clot formation. In addition to its anticoagulant activity, APC exhibits cytoprotective and anti-inflammatory effects, contributing to vascular integrity and endothelial health.
Contact us if you would like to obtain small amounts of single or multiple antibodies for pilot testing. Custom antibody labeling with biotin or fluorescent tags is available upon request. Larger amounts of labeled or endotoxin-low antibody can be prepared under special order at discounted pricing.
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Human Coagulation Factors and Plasma Antigens
Human Coagulation Factors and Plasma Antigens
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Mouse Coagulation Factors and Plasma Antigens
Mouse Coagulation Factors and Plasma Antigens
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Control Antigens
Control Antigens
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NEAH
Supporting Livestock Vaccine Development to Advance Food Security Worldwide
NEAH is a vital laboratory source of the immunological tools—monoclonal and recombinant antibodies—that are the building blocks for livestock infectious disease vaccine research and development (particularly goats and sheep). To help enable our vision, NEAH and Pentland Immunologics have identified and established manufacturing service agreements with key companies including Green Mountain Antibodies. These facilities have a proven track record in the supply of curated immunological reagents for the research community. Purchase NEAH antibodies through their website here.