GMA-164
Murine Anti- Factor IX
Clone GMA-164
Background
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Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Absent or defective FIX is the cause of the X-linked recessive bleeding disorder hemophilia B. GMA-164 (13B10) binds to Factor IX and the light chain of Factor IXa in ELISA and Western blot1. It can be used in a sandwich ELISA with GMA-162. |
More Information:
Product Datasheet, pdfDescription
Species Reactivity: Human
Source: Murine
Specificity: Light chain of FIX/FIXa
Immunogen: Human FIX peptide YNSGKL(Gla)(GLA)FVQGNLGGC
Isotype: IgG1
Application
ELISA: Binds immobilized human FIX and FIXa.
Immunoblotting: Western blot detects FIX and light chain of human FIXa under reduced conditions.
Data:
