Hybridoma Technology Explained: The Backbone of Monoclonal Antibody Production

Hybridoma technology is a cornerstone of modern biomedical research and diagnostic development. It enables the large-scale production of monoclonal antibodies—highly specific proteins that recognize a single epitope on a target antigen. Whether you’re working in basic research, therapeutic development, or in vitro diagnostics, understanding how hybridomas work can inform better decisions around antibody sourcing and […]

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How Mouse Monoclonal Antibodies Are Made: A Step-by-Step Overview

Monoclonal antibodies have become indispensable tools in biomedical research, diagnostics, and therapeutic development. Among the various production methods, the use of mouse models remains a gold standard for generating high-affinity, antigen-specific monoclonal antibodies. In this article, we walk through how monoclonal antibodies are made, focusing specifically on the well-established process of mouse monoclonal antibody development […]

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Choosing the Right Antibody Production Partner in the U.S.

Selecting a trusted provider for custom antibody production in the USA is a pivotal step in ensuring the success of your research, diagnostics, or therapeutic development. Whether you’re looking for high-specificity monoclonal antibodies or high-yield polyclonal antibodies, your choice of partner directly impacts data reliability, project timelines, and downstream applications. At Green Mountain Antibodies, we […]

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Recombinant Expression Validates De Novo Sequencing Accuracy: Trastuzumab & Anti-Factor XII Case Study

Husseini, I.3, Ruiz, A.3, Mitchell, M.1, Wenzel, R.2, Nazabal, A.3, Feldman, H.M.1 1Green Mountain Antibodies, Burlington, VT 05401 2 CovalX Analytics Inc., Woburn, MA 01801 3 CovalX Analytics SA, Martillac, France 33650 Introduction In this case study, we evaluated the accuracy and functionality of sequences derived from two reference antibodies: anti-HER2 (trastuzumab) and anti–Factor XII […]

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Mouse Monoclonal vs. Rabbit Polyclonal Antibodies: Which Is Right for Your Research?

Selecting the appropriate antibody—mouse monoclonal or rabbit polyclonal—can significantly shape the success of your experiments. Each antibody type plays a distinct role in biomedical research and diagnostics, with clear strengths and limitations. At Green Mountain Antibodies, we specialize in helping scientists and biotech teams make data-driven decisions to ensure reliable, reproducible results. What Are Mouse […]

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